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Inhalants


What Are Inhalants?

Inhalants are volatile substances that produce chemical vapors that can be inhaled to induce a psychoactive, or mind-altering, effect. Although other abused substances can be inhaled, the term "inhalants" is used to describe a variety of substances whose main common characteristic is that they are rarely, if ever, taken by any route other than inhalation. This definition encompasses a broad range of chemicals found in hundreds of different products that may have different pharmacological effects. As a result, precise categorization of inhalants is difficult. One classification system lists four general categories of inhalants - volatile solvents, aerosols, gases, and nitrites - based on the form in which they are often found in household, industrial, and medical products.


Inhalants fall into the following categories:


Solvents


Volatile solvents are liquids that vaporize at room temperatures. They are found in a multitude of inexpensive, easily available products used for common household and industrial purposes. These include paint thinners and removers, dry-cleaning fluids, degreasers, gasoline, glues, correction fluids, and felt-tip marker fluids.

Inhalant abuse

Volatile solvents are liquids that vaporize at room temperatures. They are found in a multitude of inexpensive, easily available products used for common household and industrial purposes. These include paint thinners and removers, dry-cleaning fluids, degreasers, gasoline, glues, correction fluids, and felt-tip marker fluids.


- Industrial or household solvents or solvent-containing products, including paint thinners or removers, degreasers, dry-cleaning fluids, gasoline, and glue.
- Art or office supply solvents, including correction fluids, felt-tip-marker fluid, and electronic contact cleaners


Gases


Gases include medical anesthetics as well as gases used in household or commercial products. Medical anesthetic gases include ether, chloroform, halothane, and nitrous oxide, commonly called "laughing gas." Nitrous oxide is the most abused of these gases and can be found in whipped cream dispensers and products that boost octane levels in racing cars. Household or commercial products containing gases include butane lighters, propane tanks, whipped cream dispensers, and refrigerants.


- Gases used in household or commercial products, including butane lighters and propane tanks, whipped cream aerosols or dispensers (whippets), and refrigerant gases
- Household aerosol propellants and associated solvents in items such as spray paints, hair or deodorant sprays, fabric protector sprays, and aerosol computer cleaning products
* Medical anesthetic gases, such as ether, chloroform, halothane, and nitrous oxide ("laughing gas")


Nitrites


Nitrites often are considered a special class of inhalants. Unlike most other inhalants, which act directly on the central nervous system (CNS), nitrites act primarily to dilate blood vessels and relax the muscles. While other inhalants are used to alter mood, nitrites are used primarily as sexual enhancers. Nitrites include cyclohexyl nitrite, isoamyl (amyl) nitrite, and isobutyl (butyl) nitrite, and are commonly known as "poppers" or "snappers." Amyl nitrite is used in certain diagnostic procedures and was prescribed in the past to treat some patients for heart pain. Nitrites are now prohibited by the Consumer Product Safety ComMission, but can still be found, sold in small bottles, often labeled as "video head cleaner," "room odorizer," "leather cleaner," or "liquid aroma."


- Organic nitrites are volatiles that include cyclohexyl, butyl, and amyl nitrites, and are commonly known as "poppers." Amyl nitrite is still used for medical purposes. Volatile nitrites are often sold in small brown bottles and labeled as "video head cleaner," "room odorizer," "leather cleaner," or "liquid aroma."


Street Names

Whippets, poppers, snappers


Statistics and Trends

Inhalants are often among the first drugs that young kids use. In NIDA's 2005 Monitoring the Future study, 17.1% of 8th graders, 13.1% of 10th graders, and 11.4% of 12th graders said they had abused inhalants at least once.

Source: NIDA Infofacts: High School and Youth Trends.

Extent of Use

Initial use of inhalants often starts early. Some young people may use inhalants as an easily accessible substitute for alcohol. Research suggests that chronic or long-term inhalant abusers are among the most difficult drug abuse patients to treat. Many suffer from cognitive impairment and other neurological dysfunction and may experience multiple psychological and social problems.


Harmful irreversible effects that may be caused by abuse of specific solvents include:


- Hearing loss - toluene (spray paints, glues, dewaxers) and trichloroethylene (dry cleaning chemicals, correction fluids)


- Peripheral neuropathies, or limb spasms - hexane (glues, gasoline) and nitrous oxide (whipped cream dispensers, gas cylinders)


- Central nervous system or brain damage - toluene (spray paints, glues, dewaxers)


- Bone marrow damage - benzene (gasoline)


Serious but potentially reversible effects include:


- Liver and kidney damage - toluene-containing substances and chlorinated hydrocarbons (correction fluids, dry cleaning fluids)


- Blood oxygen depletion - aliphatic nitrites (known on the street as poppers, bold, and rush) and methylene chloride (varnish removers, paint thinners)


Health Hazards

Although they differ in makeup, nearly all abused inhalants produce short-term effects similar to anesthetics, which act to slow down the body's functions. When inhaled in sufficient concentrations, inhalants can cause intoxication, usually lasting only a few minutes.


However, sometimes users extend this effect for several hours by breathing in inhalants repeatedly. Initially, users may feel slightly stimulated. Repeated inhalations make them feel less inhibited and less in control. If use continues, users can lose consciousness.


Sniffing highly concentrated amounts of the chemicals in solvents or aerosol sprays can directly induce heart failure and death within minutes of a session of repeated inhalations. This syndrome, known as "sudden sniffing death," can result from a single session of inhalant use by an otherwise healthy young person. Sudden sniffing death is particularly associated with the abuse of butane, propane, and chemicals in aerosols.


High concentrations of inhalants also can cause death from suffocation by displacing oxygen in the lungs and then in the central nervous system so that breathing ceases. Deliberately inhaling from a paper or plastic bag or in a closed area greatly increases the chances of suffocation. Even when using aerosols or volatile products for their legitimate purposes (i.e., painting, cleaning), it is wise to do so in a well-ventilated room or outdoors.


Chronic abuse of solvents can cause severe, long-term damage to the brain, the liver, and the kidneys.

Source: NIDA Infofacts: Inhalants

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